Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ InSolution™ Wortmannin
Wortmannin is a fungal metabolite that acts as a potent, selective, cell-permeable and irreversible inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase).
MilliporeSigma™ Calbiochem™ HNMPA-(AM)3
A cell-permeable analog of HNMPA that yields the parent compound upon cleavage by cytosolic esterases.
MilliporeSigma™ Calbiochem™ SUMOylation Inhibitor III, 2-D08
A cell-permeable compound that prevents the transfer of SUMO from the E2 thioester to the substrate without affecting SUMO-activating enzyme E1 (SAE-1/2) or E2 Ubc9-SUMO thioester formation.
MilliporeSigma™ Calbiochem™ InSolution™ TLR4 Inhibitor, TAK-242
A 25 mM (2 mg/221 μL) sterile-filtered solution of TLR4 Inhibitor, TAK-242 in DMSO.
MilliporeSigma™ Calbiochem™ InSolution™ Bcl-2 Inhibitor VI, ABT-737
A 25 mM (5 mg/246 μL) solution of Bcl-2 Inhibitor VI, ABT-737 in DMSO.
MilliporeSigma™ Calbiochem™ Histone Acetyltransferase Activator, CTB
The Histone Acetyltransferase Activator, CTB, also referenced under CAS 451491-47-7, modulates the biological activity of Histone. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Calpastatin, Human, Recombinant, Domain I
Domain I of human calpastatin.
MilliporeSigma™ Calbiochem™ Cdk4 Inhibitor III
The Cdk4 Inhibitor III, also referenced under CAS 265312-55-8, controls the biological activity of Cdk4. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ IL-2Rα Antagonist
The IL-2Rα Antagonist, also referenced under CAS 1217448-66-2, controls the biological activity of IL-2Rα.
MilliporeSigma™ Calbiochem™ StemSelect™ PD 0332991
A cell-permeable, brain permeant, potent, reversible, ATP competitive inhibitor of Cdk4 and Cdk6 (IC50 = 11, 9, and 15 nM for Cdk4/D1, Cdk4/D3 and Cdk6/D2, respectively).
MilliporeSigma™ Calbiochem™ Metformin
An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia.
MilliporeSigma™ Calbiochem™ HSP70 Activator II, YM-08
A cell-permeable, neutrally charged, pyridinium-to-pyridine substituted YM-01 (Cat
MilliporeSigma™ Calbiochem™ IKK-2 Inhibitor V
The IKK-2 Inhibitor V, also referenced under CAS 978-62-1, controls the biological activity of IKK-2. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ Phosphatase Inhibitor Cocktail Set V, 50X
A 50X cocktail of four serine/threonine and tyrosine phosphatase inhibitors.
MilliporeSigma™ Calbiochem™ Serine Protease Inhibitor Cocktail Set I
The Serine Protease Inhibitor Cocktail Set I controls the biological activity of Serine Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.